Chemical Composition and Therapeutic Effects of Ammodicus leucotricus Essential Oils on Neurobehavioral Changes in Wistar Rats after Experimental Scorpion Envenomation

Abstract: Background: Our study consists of a the chemical composition essential oil administered to batch rats undergoing scorpion sting. Compared with control batches, nervous state was evaluated by several neurobehavioral tests, namely open classified, dark and light forced swimming. Materials Methods: Determination plant GC/MS its protective effect on system after exposure scorpions. Results: show that this is characterized dominance natural monoterpenoid agent Perilla aldehyde, percentage 70.12%, followed Limonene (10.10%), Methyleugenol (5.69%), alpha-Pinene (5.04%). Other compounds such as alcohol (1.90%), Beta-Pinene (0.61%), Delta-3-Carene (0.59%), Carvone (0.44%) Camphene (0.33%) were identified only in small proportion. The series tests allowed us see onset depressive state, well significant decrease locomotor activity bitten compared controls treated batch. This hypolocomotor accompanied animal’s stereotyped behaviours (curiosity, sniffing, biting, grooming) muscular tone, which explains inability explore environment. Conclusion: neuroprotective power confirmed powerful properties improve symptoms caused sting, proven tests. Keywords: Scorpion, Rat, Ammodicus leucotricus, Neurobehavioral test.